NAD+
NAD+ Cellular Longevity Formula
Direct NAD+ precursor with synergistic polyphenols for cellular energy production, DNA repair, and longevity pathway activation.
Active Ingredient Matrix
| Ingredient | Amount | Clinical Role |
|---|---|---|
| NAD+ (Nicotinamide Adenine Dinucleotide) | 500mg | Direct NAD+ delivery — Cellular energy, DNA repair, sirtuin activation |
| Quercetin | Clinical dose | Senolytic polyphenol — Cellular cleanup, inflammation modulation |
| Trans-Resveratrol | Clinical dose | Sirtuin activator — Longevity pathway support, mitochondrial biogenesis |
Mechanism of Action
- Direct NAD+ Supplementation: 500mg bioavailable NAD+ bypasses biosynthesis pathways for immediate cellular availability
- Sirtuin Activation: NAD+ + Resveratrol synergistically activate SIRT1-7 longevity enzymes
- DNA Repair: NAD+ fuels PARP enzymes responsible for single-strand DNA break repair
- Cellular Senescence: Quercetin supports clearance of senescent cells (zombie cells)
- Mitochondrial Function: NAD+ required for Complex I electron transport chain activity
Clinical Dosing Protocol
Standard Dose: 2 capsules daily
Timing: Morning on empty stomach for optimal absorption
Stacking: Highly synergistic with NMN, B-vitamins, magnesium
Duration: Minimum 60 days for cellular NAD+ repletion; 90+ days for longevity pathway optimization
Quality Standards
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Easy to take, works well, what more can you ask for?
I've been dealing with chronic fatigue for years and have tried everything from B12 shots to various adaptogens. A friend who works in functional medicine suggested I look into NAD+ supplementation specifically because of how NAD levels naturally decline as you age. I'm 49 and apparently thats right in the sweet spot where you start to really feel that decline. I chose this product because the formula seemed comprehensive - you get the NAD+ itself plus quercetin which acts as a senolytic and resveratrol which activates sirtuins. These three together create a synergistic effect that you don't get from taking NAD alone. After 6 weeks I can honestly say this is the first thing that has made a meaningful sustained difference in my energy. I'm not bouncing off the walls or anything crazy but I actually feel like a normal functioning human again instead of dragging myself through each day. My brain fog has lifted considerably too which I didn't even realize was as bad as it was until it started clearing. If your dealing with fatigue and nothing else has worked, give this an honest try for at least a month. It takes a bit to build up but when it kicks in you'll know.
Bought for general wellness. Taking 2 caps every morning with breakfast. Noticeable uplift in energy and mood.
I dont usually leave reviews but this product earned it. Feel better than I have in years. More energy better sleep clearer head. Thats all I need.
I appreciate that every ingredient and its exact dosage is right there on the label. 500mg NAD+ is a strong dose. Happy with this purchase.
