SCIENCE
Research is where every Stellar formula starts.
Stellar is built around a single discipline: published clinical research drives the formula, not the other way around. This page documents the principles that govern how research becomes product.
FOUR OPERATING PRINCIPLES
How research becomes formula.
The science discipline isn't a marketing claim. It's an operating method that gates what ships.
01 · PRIMARY
Peer-reviewed first.
We anchor to peer-reviewed clinical literature over secondary sources. Mechanism-of-action research is supporting context, not substitute evidence.
02 · DOSED
Dose is research-anchored.
Each ingredient's dose maps to the dose range studied in published clinical research — not to arbitrary RDV targets.
03 · OPTIMIZED
AI screens combinations against the literature.
Models cross-reference candidate combinations against published data — flagging conflicts, redundancies, and dose-rationale gaps before manufacturing.
04 · PUBLISHED
Per-claim source list.
Each structure/function statement on a Stellar product maps to a published reference. The list is inspectable rather than walled-off.
ON AI-FORMULATION
WHAT 'AI-FORMULATED' MEANS HERE
AI screens published research. It does not invent doses.
'AI-formulated' is one of the more abused phrases in the supplement category. At Stellar it has a specific operating meaning: large-corpus models read across published clinical research to surface ingredient combinations, dose-response relationships, and interaction signals that a human researcher would take materially longer to map.
It is a literature-screening discipline — not a generation discipline.
Every dose that ships is justified against the same published source set the AI consulted. The methodology is reviewed by Clinical Index, the lab issues the COA, and the formula is auditable end-to-end. AI accelerates the literature pass; it does not bypass it.
SHILAJIT MATRIX+
Every active. Every dose. The reasoning.
Tap any active to see why we chose the dose, the mechanism, and the studies the choice is anchored to.
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01 Shilajit fulvic complex PRIMAVIA 250mg
Why this dose
Standardized at the dose range used in human studies of fulvic-acid bioavailability and mitochondrial output, not at the trace amounts common in convenience-priced shilajit products.
Mechanism
Supports cellular energy production by contributing fulvic acid and dibenzo-α-pyrones implicated in CoQ10 transport.
Source(s)
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02 Urolithin A MITOPURE 500mg
Why this dose
Published clinical-trial dosing range that produced detectable mitophagy biomarker shifts in adults; lower doses tested in earlier studies did not reach the same biomarker shift.
Mechanism
Activates mitophagy — the cell's recycling process for damaged mitochondria.
Source(s)
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03 Nicotinamide Riboside NIAGEN 300mg
Why this dose
Matches the upper safe-and-effective dose range from human pharmacokinetics studies of NAD+ precursor supplementation.
Mechanism
Serves as a precursor for NAD+ — a cofactor required by sirtuins and mitochondrial enzymes.
Source(s)
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04 CoQ10 (ubiquinol) 100mg
Why this dose
Anchored to the dose range used in cardiovascular and bioenergetic clinical trials. Ubiquinol form is selected for higher bioavailability vs ubiquinone.
Mechanism
Electron transport in the mitochondrial respiratory chain.
Source(s)
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05 PQQ 20mg
Why this dose
Held at the dose where a 2013 human study observed inflammation and mitochondrial-related metabolism shifts.
Mechanism
Cofactor implicated in mitochondrial biogenesis; reduces mitochondrial oxidative stress in vitro.
Source(s)
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06 Astaxanthin ASTAREAL 12mg
Why this dose
Held at the upper end of the human-trial range for cardiovascular and oxidative-stress endpoints. Algae-derived to match study sourcing.
Mechanism
Lipid-phase antioxidant with reported activity in cell membranes and mitochondrial inner membrane.
Source(s)
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07 Alpha-Lipoic Acid (R-isomer) 300mg
Why this dose
R-isomer is the bioactive form. Dose anchored to clinical-trial range for mitochondrial cofactor support.
Mechanism
Cofactor for mitochondrial enzymes; recycles other antioxidants in vivo.
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08 BioPerine PIPERINE 5mg
Why this dose
Standardized at the dose used in absorption-enhancement studies for co-administered actives.
Mechanism
Inhibits intestinal glucuronidation; can increase bioavailability of co-administered ingredients.
Source(s)
PEER-REVIEWED REFERENCES
Studies our formulations are anchored to.
A non-exhaustive list of the published research that informed dose ranges, ingredient choices, and combinations across the Stellar line. Each entry links out to PubMed or the source journal.
3 of 3 references
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01
View on PubMed →
MITOCHONDRIAL RENEWAL
The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans.
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02
View on PubMed →
NAD+ METABOLISM
Nicotinamide riboside is uniquely and orally bioavailable in mice and humans.
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03
View on PubMed →
MITOCHONDRIAL FUNCTION
Dietary pyrroloquinoline quinone (PQQ) alters indicators of inflammation and mitochondrial-related metabolism in human subjects.
No references match those filters.
Citations describe the topic of each study, not Stellar product claims. Stellar formulas are dietary supplements; structure/function statements have not been evaluated by the FDA. See the full DSHEA disclaimer in the footer.
GO DEEPER
Where the science lives on this site.
METHODOLOGY
How we formulate.
The literature review, AI-optimization, dose justification, and pre-manufacturing audit pipeline.
Read methodology →RESEARCH LIBRARY
Research library.
Ingredient deep-dives, methodology essays, and the COA library — organized for the documentation-reader.
Open library →VERIFICATION
Verification chain.
Independent lab, per-batch assay set, and the COA review process that gates every release.
Read verification →READ THE WORK
The methodology is inspectable.
Read the full methodology framework, browse research by ingredient, or jump straight to a formula.